• lack of sufficient number of specialist doctors locally
• small number of practically significant clinical studies
Celiac disease a rare (1%) multi-organ autoimmune disease that affects
the intestinal mucosa of genetically predisposed people.
The lesion occurs when eating foods containing gluten.
A complication of celiac disease leads to fatal T-cell lymphoma.
• gluten ataxia
• herpetiform dermatitis
• food allergy
• wheat allergy mediated by immunoglobulin E
• contact dermatitis
• baker's asthma
• gluten-induced diarrheal syndrome
• eosinophilic esophagitis
The main risk factors for celiac disease: close relatives with celiac disease, HLA-DQ2 and HLA-DQ8 genes, other autoimmune diseases.
In 2021, Well Engineering initiated the celiac disease center's online platform. The first introduction is planned in developing countries where celiac disease is the least studied.). The first step is to develop a medical register of gluten-associated diseases.
There are dozens of celiac disease research centers around the world.
The greatest contribution to clinical studies and updating the theoretical base is made by the centers:
Chicago Medical University
Columbia University
Harvard Medical School
In advanced country, studies on gluten-associated diseases are not conducted systematically, which is due to financial and bureaucratic constraints. The Val Engineering's targeted approach overcomes socio-economic barriers to the creation of a scientific and practical platform for research work.
counseling service within the framework of the registry
In May 2022, Well Engineering completed software development and implemented the first version of the gluten-associated diseases register at the clinical base of the North-West State Medical University n.a. I.I. Mechnikov (Saint Petersburg)
Methodological and organizational reference center of the register – Interregional public organization in the field of medical development “Society of gastroenterologists and hepatologists “North-West”
The platform will provide a flexible set of tools that allows the research physician to: • Perform online patient questionnairesy
• Receive online results of laboratory tests and hardware diagnostics performed by patients within the framework of registry studies
• Process registry data as part of their own clinical studies in their personal office
• Conduct online patient counseling
• Exchange opinions online with other specialists connected to the platform
To the patient: • Consult with a specialist online
• Search for scientific data on celiac disease
Other users: • Learn about current diagnostic schemes for celiac disease
• Get all the relevant information on gluten-associated diseases
• Provide financial support to the project
online consulting
The service will improve the quality of medical care by providing a constant connection of the patient with specialized celiac disease research doctors.
The service will allow consultants to transfer donations, which will be a significant incentive for doctors to research celiac disease and connect to the online center.
An additional incentive to connect doctors to the platform is to increase the client base of patients in their region.
• to consolidate clinical data on a single platform in order to implement big data technology;
• to form a database of patients for clinical trials;
• to provide an additional source of income for physicians researching celiac disease.